How Does St. John’s Wort Work


According to the World Health Organization, depression as a common mental disorder affects more than 264 million people of all ages around the world. The patients function poorly at work, at school and in the family. At its worst, depression can lead to suicide, which is causing up to 800,000 people die every year and has become the second leading cause of death in 15-29-year-olds.

While many drugs are used to treat depression, some people prefer using natural or alternative remedies. St. John’s wort is one of them. It is a medicinal plant that has been used to treat depression for centuries.

What is St. John’s Wort

Also known as Tipton’s Weed, Perforate St. John’s wart, or Klamath weed, St John’s wort is an herb that has been used to treat mental health problems for hundreds of years. It comes from a flowering plant called Hypericum Perforatum, a plant with yellow, star-shaped flowers and five petals, mainly growing in Europe, North and South America, Eastern Asia, Australia, and New Zealand. This plant contains many active substances that are thought to affect mood, including hypericin and hyperforin. Today it has become an over-the-counter remedy that is mainly used to treat mild and moderate depression, seasonal affective disorder, mild anxiety, loss of appetite and sleep problems.

How Does St. John’s Wort Work

Research suggests that St. John’s Wort can increase the activity of brain chemicals, such as serotonin and noradrenaline, which plays an important part in regulating our mood. For a long time, investigators thought a chemical found in St. John’s wort called hypericin was responsible for its antidepression effects. However, recent studies suggest that hyperforin, adhyperforin, and several other similar chemicals may also play a larger role. They act on chemical messengers in the nervous system that regulate mood to fight against mental disorders.

Can St. John’s Wort Help Me

If you are considering trying St John’s wort as an herbal alternative to antidepressants, you can buy St John’s wort extract from a pharmacy without a prescription. Chenland MoodElite® is a specially formulated botanical blend with three traditional Chinese herbs: Hypericum perforatum, Eleutherococcus senticosus, and Paeonia suffruticosa. Its development was based on 2,000 years of Traditional Chinese Medicine history and it can effectively balance mental stress, alleviate nervousness, and enhance sleep quality.

But please noted that it is best to seek advice from your GP first. If you are unsure about treatment options, it is always useful to talk with your doctor before you make a decision.


How quickly does St John’s wort work?
It may take 3 to 6 weeks to feel any effects from St. John’s wort. Do not stop taking St. John’s wort all at once because that may cause unpleasant side effects.

Is St John’s wort safe to take?
St. John’s wort is generally considered safe when used orally in appropriate doses.

Who shouldn’t take St John’s wort?
Herbal therapies aren’t recommended for pregnant women, children, the elderly, or those with certain medical condition.

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